Nicole L La Gruta Selected Research

deoxythymidine 3',5'-bis-(p-nitrophenyl phosphate)

10/2015	Paired TCRαβ analysis of virus-specific CD8(+) T cells exposes diversity in a previously defined 'narrow' repertoire.
1/2013	Ecological analysis of antigen-specific CTL repertoires defines the relationship between naive and immune T-cell populations.
12/2010	Influenza epitope-specific CD8+ T cell avidity, but not cytokine polyfunctionality, can be determined by TCRβ clonotype.
8/2008	Terminal deoxynucleotidyltransferase is required for the establishment of private virus-specific CD8+ TCR repertoires and facilitates optimal CTL responses.
1/2006	A virus-specific CD8+ T cell immunodominance hierarchy determined by antigen dose and precursor frequencies.
4/2005	Effector CD8+ T cells recovered from an influenza pneumonia differentiate to a state of focused gene expression.
5/2004	Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific CD8+ T cell responses: correlation of cytokine profile and TCR avidity.
3/2004	Differential tumor necrosis factor receptor 2-mediated editing of virus-specific CD8+ effector T cells.

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Nicole L La Gruta Research Topics

Disease

21	Infections 01/2022 - 06/2004
18	Human Influenza (Influenza) 01/2019 - 03/2004
4	Virus Diseases (Viral Diseases) 01/2022 - 12/2002
2	Rheumatoid Arthritis 01/2021 - 11/2013
2	Autoimmune Diseases (Autoimmune Disease) 11/2017 - 10/2002
2	Celiac Disease (Celiac Sprue) 11/2015 - 05/2014
2	Neoplasms (Cancer) 12/2010 - 09/2005
1	Fibrosis (Cirrhosis) 11/2021
1	Malaria 10/2020
1	Multiple Sclerosis 11/2017
1	Lymphopenia (Lymphocytopenia) 01/2014
1	Inflammation (Inflammations) 09/2005
1	Pneumonia (Pneumonitis) 03/2004
1	Gastritis 10/2002

Drug/Important Bio-Agent (IBA)

22	EpitopesIBA 01/2021 - 03/2004
8	AntigensIBA 10/2020 - 06/2004
8	deoxythymidine 3',5'-bis-(p-nitrophenyl phosphate)IBA 10/2015 - 03/2004
7	Peptides (Polypeptides)IBA 10/2020 - 03/2004
6	NucleoproteinsIBA 01/2019 - 05/2004
6	AcidsIBA 01/2019 - 03/2004
5	CytokinesIBA 01/2020 - 05/2004
4	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2015 - 03/2004
3	HLA Antigens (Human Leukocyte Antigens)IBA 11/2017 - 11/2013
3	Amino Acids FDA Link 01/2013 - 04/2005
2	Histocompatibility Antigens Class IIBA 10/2020 - 12/2010
2	VaccinesIBA 01/2019 - 11/2007
2	Glutens (Glutelin)IBA 11/2015 - 05/2014
2	GliadinIBA 11/2015 - 05/2014
2	Proteins (Proteins, Gene)FDA Link 10/2015 - 01/2013
2	AutoantigensIBA 11/2013 - 10/2002
2	Bromodeoxyuridine (BrdU)IBA 01/2013 - 07/2012
2	Glycoproteins (Glycoprotein)IBA 01/2006 - 03/2004
2	Indicators and Reagents (Reagents)IBA 06/2004 - 12/2002
1	ChromatinIBA 01/2022
1	C.I. direct red 80IBA 11/2021
1	CollagenIBA 11/2021
1	HLA-DR4 Antigen (HLA DR4 Antigen)IBA 01/2021
1	ribosomal protein L6IBA 10/2020
1	Ribosomal Proteins (Ribosomal Protein)IBA 10/2020
1	Peptide LibraryIBA 11/2015
1	HLA-DRB1 Chains (HLA DRB1)IBA 11/2013
1	Antiviral Agents (Antivirals)IBA 01/2013
1	CD40 Ligand (CD40L)IBA 01/2013
1	LipopeptidesIBA 08/2011
1	SolventsIBA 08/2010
1	Granzymes (Granzyme)IBA 09/2008
1	PerforinIBA 09/2008
1	Immunologic Factors (Immunomodulators)IBA 02/2007
1	Interleukin-11 (Interleukin 11)IBA 09/2005
1	Matrix Metalloproteinases (MMPs)IBA 09/2005
1	InterleukinsIBA 09/2005
1	Interleukin-6 (Interleukin 6)IBA 09/2005
1	LigandsIBA 09/2005
1	Arginine (L-Arginine)FDA Link 04/2005
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2004
1	Type II Tumor Necrosis Factor ReceptorsIBA 03/2004
1	Coloring Agents (Dyes)IBA 12/2002
1	H(+)-K(+)-Exchanging ATPase (Hydrogen, Potassium ATPase)IBA 10/2002
1	Adenosine Triphosphatases (ATPase)IBA 10/2002

Therapy/Procedure

1	Gluten-Free Diet 11/2015